Please check back often for new openings.
Our benefits include:
- Medical insurance
- Dental insurance
- Life/AD&D insurance
- Long-term disability insurance
- 401(k) plan
- 11 paid holidays
- 15 vacation days
Please send your resume to careers@mersana.com or
Mersana Therapeutics, Inc.
Attn: Human Resources
840 Memorial Drive
Cambridge, MA 02139
Mersana is proud to be an equal opportunity employer.
Senior Clinical Program Manager - (reference code: SCMP)
November 24, 2009
Mersana Therapeutics employs its biodegradable polymer platform (Fleximer®) to create new and better medicines. We are advancing our own clinical-stage pipeline of novel compounds with the potential to address multiple oncology indications. We also leverage the versatility of Fleximer through partnerships to overcome the safety, efficacy, and delivery challenges of nucleic acids, biologics, and small molecules in numerous therapeutic areas.
We are seeking an experienced, enthusiastic project leader who thrives in a fast-paced work environment and who will become an integral member of our Clinical Development group. Reporting to the Chief Medical Officer, the Senior Clinical Program Manager's primary function is to lead the management of the operational aspects of clinical programs. The Senior Clinical Program Manager has the experience to execute a clinical plan for an oncology drug development candidate so that compounds are developed in a manner that is timely, within budget, and to a high medical and scientific standard.
Specific Responsibilities:
- Maintains a daily, "hands-on" approach to the management of the external vendors, CROs, and clinical sites - supporting site budget negotiations and investigator contracting, site initiation, tracking patient enrollment, site monitoring, and site close-out.
- Manages the planning, tracking and adherence to allocated budget and timelines.
- Resolves issues affecting clinical program and operations; plans contingencies for potential concerns.
- Contributes to the development and review of protocols to achieve the aims of the development plan. Collaborates with relevant internal and external (CROs) groups on the initiation and execution of clinical studies.
- Works with the Chief Medical Officer and clinical development group, study sites, and CRO to ensure operational feasibility of protocols and programs for successful implementation.
- Assists in the preparation of responses to regulatory agencies regarding program development issues.
- Adheres to Code of Federal Regulations, ICH Guidelines and all other applicable ethical, regulatory, and clinical standards.
- Supports the production of draft regulatory documents and study reports. Ensures medical/scientific quality of the documents and accordance with regulatory guidelines and the overall development strategy.
- Contributes to preparation of abstracts, manuscripts, and external presentations.
- Remains current in the scientific/clinical knowledge for the compounds under clinical investigation in the company.
- Establishes and fosters an atmosphere conducive to teamwork within the company and with outside project participants.
Other requirements:
- Working knowledge of GCPs, ICH Guidelines, and federal regulations
- Knowledge of clinical drug development and associated processes
- Must have extensive working knowledge of Microsoft Office Products including Outlook, Word, Excel and PowerPoint and Project
- Excellent organizational, written and verbal communication skills
Education:
- RN or BS/MS or equivalent in life sciences or BA with appropriate clinical research experience
Experience:
- At least 7 years of experience in the management of clinical research programs in a CRO, biotech or pharmaceutical company; expertise in oncology trials a plus. Extensive knowledge and experience managing operational aspects of clinical trials is essential.
- Experience in supporting IND, protocol, and IB development
- Experience working with medical professionals in oncology a plus
Special Requirements:
Salary:
- Salary and title commensurate with experience and responsibility.
Scientist/Senior Scientist - Bioanalytical Chemistry
February 2010
Mersana Therapeutics employs its biodegradable polymer platform (Fleximer®) to create new and better medicines. We are advancing our own clinical-stage pipeline of novel compounds with the potential to address multiple oncology indications. We also leverage the versatility of Fleximer through partnerships to overcome the safety, efficacy, and delivery challenges of nucleic acids, biologics, and small molecules in numerous therapeutic areas.
Mersana is seeking a Scientist/Senior Scientist - Bioanalytical Chemistry. The company is backed by strong investors and is developing a pipeline of products including chemotherapeutic, anti-angiogenesis and siRNA-based agents.
Key Responsibilities:
The candidate will work independently with minimal supervision, and within a group, providing expertise, guidance, and training to junior staff scientists. Responsibilities may include but are not limited to:
- Design, development and validation of analytical/bioanalytical assays and methods for small molecule and polymer based (peptide, protein, RNA) therapeutic agents utilizing HPLC, LC/MS/MS, spectroscopic and wet chemistry techniques. Application of developed methodologies for the rapid and accurate analysis of active compounds in biological matrices, including biological fluids and tissues.
- Interpretation of experimental data and maintenance of detailed records of experimental observations. Preparation of written protocols and communication of results in technical reports as well as written contributions to regulatory documents.
- Initiation and oversight of a variety of collaborations with external vendors, including design and oversight of non-clinical pharmacokinetic and ADME testing of drug candidates
- Participation on project teams with Research and Clinical / Regulatory colleagues to establish and meet team objectives; presentation of results at internal company meetings as well as at National/International Research Meetings
Education/Experience:
- A Ph.D. degree in Analytical Chemistry, or related field, with 2+ years post-doctoral or industry experience in LC/MS/MS based bioanalytical method development with a proven track record of research activities in the field of in vitro/in vivo metabolism, metabolite ID, pharmacokinetics, and/or drug interaction studies.
Qualifications:
- Candidate must be a flexible, self-motivated problem solver and collaborative team player with a strong track record of accomplishment. Strong communication, organizational and presentation skills a must.
Compensation and Benefits:
Commensurate with experience and level of responsibility. Includes base salary, bonus, and stock option program awards.
Scientist - Organic Chemistry
February 2010
Mersana Therapeutics employs its biodegradable polymer platform (Fleximer®) to create new and better medicines. We are advancing our own clinical-stage pipeline of novel compounds with the potential to address multiple oncology indications. We also leverage the versatility of Fleximer through partnerships to overcome the safety, efficacy, and delivery challenges of nucleic acids, biologics, and small molecules in numerous therapeutic areas.
Mersana is seeking a synthetic organic chemist to join our growing chemistry group to develop new RNA interference based therapeutics. The successful candidate will be responsible for the synthesis of oligonucleotides (ON) and ON-conjugates to support the development of new siRNA delivery platforms. The company is backed by strong investors and is developing a pipeline of products including chemotherapeutic, anti-angiogenesis and siRNA-based agents.
Key Responsibilities:
- Synthesis and analytical characterization of novel ONs and ON-conjugates to support internal development and preclinical evaluation of lead compounds
- Process development, optimization and documentation
- Interpretation of experimental data and maintenance of detailed records of experimental observations. Preparation of written protocols and communication of results in technical reports.
- Use technical expertise to design, execute and interpret results of experiments and contribute to project strategies
Education/Experience:
- Ph.D. in Chemistry, or related field, with 2+ years of post-doctoral or industry experience.
- The candidate must have experience in multi-step organic synthesis including state-of-the-art purification and analytical methods (HPLC, LC/MS, NMR, UV, fluorescent spectroscopy); previous experience with automated ON synthesis, SPPS, bioconjugate chemistry and macromolecules (proteins, carbohydrates, DNA/RNA) is a plus.
Qualifications:
- Candidate must be a flexible, self-motivated problem solver and collaborative team player with a strong track record of accomplishment. Strong communication, organizational and presentation skills a must.
Compensation and Benefits:
Commensurate with experience and level of responsibility. Includes base salary, bonus, and stock option program awards.
