Careers

At Mersana, we all share a singular passion and vision: To dramatically improve the lives of people with cancer. We know that what each and every one of us does matters and that our success depends on our ability to work together. We believe we are at our best as a company when our employees are thriving and foster a culture that provides opportunities to grow and develop professionally, while also having fun. 

If you share our passion to deliver an evolutionary leap in cancer patient care and our drive to tackle difficult challenges in a dynamic and collaborative environment, then please submit your resume or CV to careers@mersana.com.


ANALYTICAL CHEMISTRY

Principal/Senior Scientist – Protein Characterization ADC - mAb

Mersana has an exciting new opportunity for a Senior/Principal Scientist working with our growing analytical chemistry team.

Key Responsibilities:

  • Responsible for protein analysis and protein characterization working with ADC technology.
  • Perform RP/IEX/SEC HPLC, LC/MS, CE/icIEF and spectrophotometrybased testing of antibodies and antibody-drug conjugates.
  • Perform HPLC and LC/MS analyses and routine maintenance on analytical instrumentation including Shimadzu and Agilent HPLC systems, ThermoFisher Q-Exactive LC MS/MS system.
  • Participate in the development/evaluation of new analytical methods to support our growing drug pipeline and assist our chemistry and bioconjugation groups with their sample preparation and analysis.
  • Development of high throughput methods for screening of antibodies and ADCs for various CQAs
  • Serve as an effective representative of Analytical Chemistry by clear communication, problem-solving and delivering on team goals as a member of Discovery pipeline and technology project teams
  • Schedule, implement method development and research activities; maintain accurate laboratory records and notebooks; follow analytical procedures and validation protocols in compliance with regulatory requirements and industry standards; write analytical reports and SOPs.
  • Develop and qualify new analytical methods for research materials evaluation.
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Principal/Senior Scientist, Protein Characterization ADC - mAb (CMC)

What’s in it for you?

In this role, you’ll have an opportunity to support the analytical characterization of Mersana’s Antibodies and ADCs within our CMC Analytical Chemistry group.  Since we are on the cutting edge of a new therapeutic category with its own unique testing requirements, we will take your existing expertise in analytical development, method development, validation/qualification and transfer, and complement it with our knowledge of polymer and small molecule chemistry.  You’ll also have an opportunity to form close partnerships with CMOs, CROs and internal stakeholders.  If you are passionate about our science and a curious scientist who enjoys being creative and not afraid to be challenged, this is a great opportunity to have an impact on Mersana’s unique novel platform.  We will work as a team to expand our knowledge base of our ADCs in order to enable their evolution towards optimized cancer therapies.  You will be immersed in a learning organization, with a need to bring an open mind and an interest in mastering this new therapeutic space at a rapid pace.   As part of a growing company you will have the potential to hire and mentor staff and build processes that will drive innovation, teamwork and efficiency within the organization. 

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BIOCONJUGATION

Director/Associate Director, Bioconjugation

What’s in it for you?

In this role, you will lead Discovery bioconjugation activities at Mersana. You will initiate and shape close partnerships with Chemistry, Biology, Analytical and CMC colleagues within a framework of projects aimed at discovery of ADC clinical candidates. Your leadership will critically influence Mersana’s pipeline at an exciting time in our company’s journey. You will report to the Senior Director, Discovery Chemistry and Bioconjugation and will be a member of the Discovery Chemistry Leadership Team.

You will champion the development of new conjugation technologies integrated with the novel discovery platforms being developed by Mersana. You will also have the opportunity to identify and implement improvements to Mersana current platforms. You will effectively influence the strategic direction of scientific pursuit at Mersana by applying and sharing your Antibody Drug Conjugate science knowledge and experience. You will clearly communicate strategies, progress and challenges to key stakeholders. You will have the opportunity to manage direct reports and to ensure their professional growth as well as project success.

 

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Senior Scientist, Bioconjugation

What’s in it for you?

In this role, you will have an opportunity to contribute to the advancement of new ADC platform technologies, bioconjugation technologies, and pipeline candidates. Specifically, you will drive innovation and optimization related to the preparation, purification and characterization of novel ADCs for Mersana and its partners.  In this role, you will have the opportunity to initiate, direct and execute scientific research aimed at innovation and bioconjugation process improvements. Your expertise in working with protein conjugates will add value to our team, expanding our knowledge base of our ADCs and enable their timely progression towards breakthrough cancer therapies.  You will be immersed in a learning and team-focused environment, where demonstration of an open mind and interest in mastering this new therapeutic space, and close collaboration with fellow team members are keys to your success. 

 

As part of a growing company, you will have the ability to mentor junior staff.  You will represent Bioconjugation and work closely with teammates in Chemistry, Biology, and Analytical Chemistry, both internally and with collaboration partners, on technology and pipeline teams to advance new technologies and ADCs towards the clinic. 

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BIOLOGY

Senior/Principal Scientist, Biology Project Team Leader

What’s in it for you?

In this role, you will have the opportunity to drive oncology drug discovery projects and define antibody-drug conjugates (ADCs) for clinical development by applying rigorous scientific thought, experimentation and leadership. You will make a great impact on Mersana’s pipeline at this extraordinary stage of the company’s development. You will report to the Senior Director, Head of Biology and join the Biology Leadership Team.

 

You will lead cross-functional discovery teams to establish strategy, identify key go/no go experiments, and design, execute, supervise experiments and interpretation of results. Ultimately you will deliver clinical development candidates with rich preclinical data packages that include in vitro and in vivo pharmacology, and author regulatory documents to support clinical development. You will clearly communicate strategy, progress, challenges to management and key stakeholders; represent the company at scientific meetings and in high-impact publications. You will have the opportunity to manage direct report(s) to ensure their professional growth as well as project success.

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Scientist/Senior Scientist, Cancer Immunotherapy Drug Discovery

What’s in it for you?

We are seeking a dynamic scientist with immunology or immuno-oncology experience to join a team of scientists that are developing Antibody Drug Conjugates (ADCs) spanning target identification, lead selection, and development into clinical candidates. In this role, you will have the opportunity to impact Mersana’s growing pipeline of leading edge ADCs through discovering and delivering innovative strategies aimed at modulating tumor immune responses. You will utilize multidisciplinary approaches to select targets for Mersana’s ADC platforms and support chemistry teams in discovery and optimization of novel ADC platforms geared towards expanding Mersana’s drug discovery pipeline. This is a unique opportunity for a highly motivated PhD scientist with a passion to develop cancer therapeutics to immerse her/himself into pharmaceutical drug development from concept to early clinical development.  What you will bring to Mersana is a deep understanding of tumor immunology, a mechanism driven approach to drug development, strong abilities in critical thinking, research/technical skills, independence, flexibility, and willingness to learn and implement new technologies.

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DMPK

Associate Scientist, DMPK/Clinical Pharmacology

What’s in it for you?

In this role, you will have an opportunity to work closely with both clinical and nonclinical peers and grow your experience in DMPK and clinical pharmacology. This role will have a great impact to Mersana at this extraordinary stage of the company’s development, specifically, you will assist in non-clinical & clinical PK, PD data analysis, and spend some of your time interacting with internal and external partners to manage reagents & documents. You will be immersed in a learning organization, where you can bring an open mind and be ready to learn new concepts and tools. 

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QUALITY ASSURANCE

Director, QA Operations

What’s in it for you?

  • In this role, you will have an opportunity to build a phase appropriate Quality Management System (QMS)
  • You will make quality decisions that will influence the success and progression of Mersana’s clinical pipeline
  • You will have the opportunity to promote and advance the quality culture at Mersana
  • You will have the opportunity to create an influential and collaborative relationship for Quality across Mersana
  • You will be accountable for the Quality Assurance Operations function and batch decisions for Mersana’s clinical products
  • You will have the opportunity to work with and learn from technical experts internal and external to Mersana through collaboration and partnerships
  • As part of a growing company you will have the ability to mentor staff and build processes that will drive innovation, teamwork and efficiency within the organization
  • To be successful, you must have broad experience in a Quality Assurance role supporting; GLP, GCP, GMP and enjoy working in a fast-paced GxP environment
  • This role reports directly to the Head of Quality. Together, you will promote a culture of quality and operational excellence
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